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NEWS
2022-06
"paPAML: An Improved Computational Tool to Explore Selection Pressure on Protein-Coding Sequences" by Lynn Ogoniak, Norbert Grundmann and others
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2022-05-14
"Mobilome of Apicomplexa Parasites" by Rodriguez and Makalowski has been published by Genes.
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2022-04-27
"Software evaluation for de novo detection of transposons" by Rodriguez and Makalowski has been published by Mobile DNA.
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2022-04-01
"From telomere to telomere: The transcriptional and epigenetic state of human repeat elements” by T2T consortium has been published by Science.
Goto
2022-02-12
"Global research alliance in infectious disease: a collaborative effort to combat infectious diseases through dissemination of portable sequencing” by GRAID consortium that IoB is part of has been published by BMC Research Notes.
Goto
2021-08-05
Congratulations to Reza and Matias on the excellent contribution on TE-driven DNA transductions in the human genome
Goto
2021-05-29
"Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer" was published by MDPI
Goto
Evolution of formins

Formins are multidomain proteins which are implicated in a wide range of actin-based processes, including cell polarization, cytokinesis, and embryonic development in all eukaryotic species studied so far. The signature sequence of formins is the formin homology-2 (FH2) domain, which is crucial for actin nucleation. Although six different formin protein families have been described so far, there is no comprehensive understanding of the actual number of genes encoding for the FH2 domains in different metazoan genomes. We systematically scan complete genomes for FH2-domain coding genes and study evolutioary history of this gene family.

2018-11-15 11:50