NEWS
2023-08-28
"The complete sequence of a human Y chromosome” by T2T Consortium
has been published by Nature
View
2022-10-28
"The new uORFdb: integrating literature, sequence, and variation
data in a central hub for uORF research” by Felix Manske, Lynn Ogoniak,
Norbert Grundmann and Wojciech Makałowski has been published by
Nucleic Acids Research.
View
2022-07-08
"A Map of 3' DNA Transduction Variants Mediated by Non-LTR
Retroelements on 3202 Human Genomes” by Reza Halabian and Wojciech
Makałowski has been published by Biology.
View
2022-06
"paPAML: An Improved Computational Tool to Explore Selection
Pressure on Protein-Coding Sequences" by Lynn Ogoniak, Norbert
Grundmann and others
View
2022-05-14
"Mobilome of Apicomplexa Parasites" by Rodriguez and Makalowski
has been published by Genes.
View
2022-04-27
"Software evaluation for de novo detection of transposons" by
Rodriguez and Makalowski has been published by Mobile DNA.
View
2022-04-01
"From telomere to telomere: The transcriptional and epigenetic
state of human repeat elements” by T2T consortium has been
published by Science.
Goto
2022-02-12
"Global research alliance in infectious disease: a collaborative
effort to combat infectious diseases through dissemination of
portable sequencing” by GRAID consortium that IoB is part of has
been published by BMC Research Notes.
Goto
2021-08-05
Congratulations to Reza and Matias on the excellent contribution on
TE-driven DNA transductions in the human genome
Goto
2021-05-29
"Somatic Functional Deletions of Upstream Open Reading
Frame-Associated Initiation and Termination Codons in Human
Cancer" was published by MDPI
Goto
Evolution of formins
Formins are multidomain proteins which are implicated in a wide range of actin-based processes, including cell polarization, cytokinesis, and embryonic development in all eukaryotic species studied so far. The signature sequence of formins is the formin homology-2 (FH2) domain, which is crucial for actin nucleation. Although six different formin protein families have been described so far, there is no comprehensive understanding of the actual number of genes encoding for the FH2 domains in different metazoan genomes. We systematically scan complete genomes for FH2-domain coding genes and study evolutioary history of this gene family.
2018-11-15 11:50
