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2020-03-18
"RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells" by Kouzel at al. has been published by Scientific Reports.
Goto
2020-03-05
"Enhancer occlusion transcripts regulate the activity of human enhancer domains via transcriptional interference: a computational perspective" by Pande et al. has been published by Nucleic Acid Research
Goto
2020-01-21
Congratulations Felix Manske on getting the GBM-Masterpreis!
Goto
2019-12-18
"Emergence and evolution of ERM proteins and merlin in metazoans" by Shabardina et al. has been published by Genome Biology and Evolution
Goto
2019-12-16
"Loss of ADAMTS19 causes progressive non-syndromic heart valve disease" by Wünnemann et al. has been published by Nature Genetics
Goto
2019-11-04
Congratulations Matias for the "Best Poster" award at the X International Conference on Bioinformatics - Celebrating the 10th Anniversary of SoIBio and 10th Anniversary of the Master in Bioinformatics Uruguay.
2019-10-03
"Statins: Complex outcomes but increasingly helpful treatment options for patients" by Mohammadkhani, Korsching et al. has been published by European Journal of Pharmacology.
Goto
2019-10-01
Congratulations to Marten - another successful Master of Science.
2019-09-16
"An integrated genome-wide multi-omics analysis of gene expression dynamics in the preimplantation mouse embryo" by Israel, Makalowski et al. has been published by Scientific Reports.
Goto
Evolution of formins

Formins are multidomain proteins which are implicated in a wide range of actin-based processes, including cell polarization, cytokinesis, and embryonic development in all eukaryotic species studied so far. The signature sequence of formins is the formin homology-2 (FH2) domain, which is crucial for actin nucleation. Although six different formin protein families have been described so far, there is no comprehensive understanding of the actual number of genes encoding for the FH2 domains in different metazoan genomes. We systematically scan complete genomes for FH2-domain coding genes and study evolutioary history of this gene family.

2018-11-15 11:50