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NEWS
2021-08-05
Congratulations to Reza and Matias on the excellent contribution on TE-driven DNA transductions in the human genome
Goto
2021-05-29
"Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer" was published by MDPI
Goto
2020-12-04
Genome Assembly and Annotation of the California Harvester Ant Pogonomyrmex californicus (Buckley, 1867)
Goto
2020-09-10
"GenoTypeMapper: graphical genotyping on genetic and sequence-based maps" by Deblieck, Fatiukha, Grundmann et al. has been published by Plant Methods.
Goto
2020-03-18
"The multi-comparative 2-n-way genome suite" by Churakov, Zhang, Grundmann et al. has been published by Genome Research.
Goto
2020-03-18
"RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells" by Kouzel at al. has been published by Scientific Reports.
Goto
2020-03-05
"Enhancer occlusion transcripts regulate the activity of human enhancer domains via transcriptional interference: a computational perspective" by Pande et al. has been published by Nucleic Acid Research
Goto
2020-01-21
Congratulations Felix Manske on getting the GBM-Masterpreis!
Goto

Matias Rodriguez

Matias R
I started a doctorate at the Institute of Bioinformatics, University of Münster, in April 2019 under the supervision of Prof. Wojciech Makałowski. I graduated as Lic. in Biochemistry (2013) and M.Sc in Bioinformatics (2018) from Universidad de la República (UdelaR), Uruguay.
Current project:
My research project consists in the identification and characterization of transposable elements (TEs) in all currently available apicomplexan genomes (67 genomes as of April 2019). The research involves developing a pipeline for an accurate classification and annotation of TEs and the evolutionary analysis of these elements considering their genomic context and their impact in the genome. For easy access to the results of this research I'm developing a database and web application along with interactive data visualizations.
Experience:
I worked as research assistant at the Faculty of Science of UdelaR (2011-2016) in the assembly and annotation of two Trypanosoma vivax strains studying the genomic evolution and adaptation to the American continent. As part of this project I explored genome compartmentalization and gene expression during antigenic variation.
I also worked as technical assistant at the Institut Pasteur of Montevideo (2017-2018) in the assembly and annotation of three Trypanosoma cruzi strains and in the development of a web application to explore and visualize these assemblies.
Internships:
- Functional Genomics Laboratory, Biotechnology Department, University of Verona, Italy, (June 2014) working with trypanosome RNAseq datasets.
- GENOPOM, Department of Agricultural Science, University of Naples Federico II, Italy, (October 2017) developing interactive plots for the analysis of tomato transposons.
Grants:
I got a Master Program Grant from ANII (2014-2016) and a CSIC Research Grant (2014), both from Uruguay.
Since 2019 I've got funding from DAAD Research Grant/Doctoral Programmes in Germany for a four-year research plan.
Publications:
  • Greif G., Rodriguez M., Bontempi I., Robello C., Alvarez-Valin F. (2021) "Different kinetoplast degradation patterns in American Trypanosoma vivax strains: Multiple independent origins or fast evolution?" Genomics doi.org/10.1016/j.ygeno.2020.12.037
  • Berná L., Rodriguez M., Chiribao ML, Parodi A., Rijo G., Alvarez-Valin F., Robello C. (2018) "Expanding an expanded genome: long-read sequencing of Trypanosoma cruzi." Microbial Genomics doi.org/10.1099/mgen.0.000177
  • Berná L., Chiribao ML., Greif G., Rodriguez M., Robello C., & Alvarez-Valin F. (2017) "Transcriptomic analysis reveals that metabolic switch and surface remodeling are key processes for stage transition in Trypanosoma cruzi." PeerJ 5:e3017doi.org/10.7717/peerj.3017
  • Greif G., Rodriguez, M., Reyna-Bello A., Robello C., & Alvarez-Valin F. (2015) "Kinetoplast adaptations in American strains from Trypanosoma vivax" Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 773, 69-82.doi.org/10.1016/j.mrfmmm.2015.01.008
  • Greif G., Ponce de León M., Lamolle G., Rodriguez M., Piñeyro D., Tavares-Marques L., Reyna-Bello A., Robello C., Alvarez-Valín F. (2013) "Transcriptome analysis of the bloodstream stage from the parasite Trypanosoma vivax" BMC Genomics 14, 149.doi.org/10.1186/1471-2164-14-149
2021-01-11 15:22