The IoB consists of two independent research groups: Cancer & Complex Systems Research (Prof. Korsching) and the emeriti group Comparative Genomics (Prof. Makalowski) here on the page.
The Cancer & Complex Systems Research (CCSR) group focuses on analyzing the complexity and regulatory systems of biological cells. The primary research effort of the independent group is specifically centered around expression networks and how they contribute to the robust and adaptive cellular system. To achieve this, we utilize the analysis of expression/sequence datasets and conduct accompanying theoretical studies. The mechanistic insights generated through our research will be particularly useful in understanding the formation and progression of cancer in breast, bone, and other types of cancers. The development of appropriate software tools complements our work and is based on R, C, and C++ (e.g., MAF, DenovoFusion).
Comparative Genomics group research spans wide range of topics related to broadly understood genomic evolution. We are interested in basic processes that shape our genomes such as gene families evolution (globins, mitochondrial outer membrane proteins), genome structure (Genomic ScrapYard, U12-type introns), and host-parasite interactions (Apicomplexa population genetics, fruit bat genomes). We are also engaged in building software and databases (TinT, TEclass, ACTransDB, just to name few).
For further information, choose the CCSR page or the right panel for some specific project descriptions.
External collaborators
- Dr. Michele Boiani, Max-Planck Institute for Molecular Medicine
- Prof. Georg Fuellen, University of Rostock
- Prof. Martin Frith, University of Tokyo
- Prof. Juergen Gadau, University of Muenster
- Prof. Hanna Kmita, Adam Mickiewicz University
- Prof. Izabela Makałowska, Adam Mickiewicz University
- Dr. Juergen Schmitz, University of Muenster
- Prof. Yutaka Suzuki, University of Tokyo
- Dr. Klaus Wethmar, University of Muenster
- Dr. Junya Yamagishi, Hokkaido University
- Dr. Christof Bernemann - UKM Münster, Urology
- Dr. Klaus Wethmar - Medizinische Klinik A - Hämatologie, Hämostaseologie, Onkologie, PneumologieUrology
- Dr. Junya Yamagishi - Research Center for Zoonosis Control, Hokkaido University
