WWU Münster UKM
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NEWS
2021-08-05
Congratulations to Reza and Matias on the excellent contribution on TE-driven DNA transductions in the human genome
Goto
2021-05-29
"Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer" was published by MDPI
Goto
2020-12-04
Genome Assembly and Annotation of the California Harvester Ant Pogonomyrmex californicus (Buckley, 1867)
Goto
2020-09-10
"GenoTypeMapper: graphical genotyping on genetic and sequence-based maps" by Deblieck, Fatiukha, Grundmann et al. has been published by Plant Methods.
Goto
2020-03-18
"The multi-comparative 2-n-way genome suite" by Churakov, Zhang, Grundmann et al. has been published by Genome Research.
Goto
2020-03-18
"RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells" by Kouzel at al. has been published by Scientific Reports.
Goto
2020-03-05
"Enhancer occlusion transcripts regulate the activity of human enhancer domains via transcriptional interference: a computational perspective" by Pande et al. has been published by Nucleic Acid Research
Goto
2020-01-21
Congratulations Felix Manske on getting the GBM-Masterpreis!
Goto

Dr. Ronaldo Schuch

Tradition Talk

Transcription factor (TF) binding pattern and arrangement within transcriptional start sites are crucial for the regulation of expression levels of various tumor related genes. A widely used method to analyze transcription factor binding sites (TFBSs) in vivo is the chromatin immunoprecipitation (ChIP). However, this method does not enable the individual investigation of neighboring TFBSs due to its unspecific DNA fragmentation technique. We established an improved ChIP technique which allows the detection of single TFBSs even in a complex of multiple adjacent binding motives of the same TF. We applied this new method to study the regulation of EGFR.

2011-06-28 15:10