WWU Münster UKM
Congratulations to Reza and Matias on the excellent contribution on TE-driven DNA transductions in the human genome
"Somatic Functional Deletions of Upstream Open Reading Frame-Associated Initiation and Termination Codons in Human Cancer" was published by MDPI
Genome Assembly and Annotation of the California Harvester Ant Pogonomyrmex californicus (Buckley, 1867)
"GenoTypeMapper: graphical genotyping on genetic and sequence-based maps" by Deblieck, Fatiukha, Grundmann et al. has been published by Plant Methods.
"The multi-comparative 2-n-way genome suite" by Churakov, Zhang, Grundmann et al. has been published by Genome Research.
"RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells" by Kouzel at al. has been published by Scientific Reports.
"Enhancer occlusion transcripts regulate the activity of human enhancer domains via transcriptional interference: a computational perspective" by Pande et al. has been published by Nucleic Acid Research
Congratulations Felix Manske on getting the GBM-Masterpreis!
Dipl. Inf. Norbert Grundmann
The biggest communication problem is we do not listen to understand - we listen to reply
Norbert G
I am responsible for soft- and hardware at this institute. You know, this is a never ending story and full of surprises. Previously I was working as an administrator at university, as a consultant and in an insurance company - mainly in software engineering and implementation. Much of my work belongs to genetic projects with the focus on software solutions for scientific questions.
Work and visions
As I started my work at this Institute I began to learn more about genetics and the underlaying software. For different projects I designed and implemented tools, like SCA for codon analsis and TinT for time evaluation of transpositions. Actually I am working on a tool called "Genome Presence Absence Compiler" gpac. One thing that I have learned: software is only as good as the team that created it. Maybe we will work on the road together? :-)
Along this I am very interested in the Unix system FreeBSD and happy that many of our server are switched to BSD :-) I know *BSD needs in some areas more "hands-on", installation and background knowledge, but the result is a small, functional and stable system. Even on desktops! And it works and works :) I like this approach very much and I dislike the (only) GUI centric system administration on many other systems. What about the situation if the GUI does not work? Even I like and use *BSD systems I am not an enemy of others. But I think people, who claim that *BSD does not work, never took time to use it! I made also experiences with Linux, OsX and Windows - and that is the reason why I switched completely to *BSD :) And by the way, there are many interesting operating systems available so far, which are very impressive and definitly worth to check them out - and maybe switch over :)
FreeBSD FreeBSD is an operating system used to power modern servers, desktops, and embedded platforms. A large community has continually developed it for more than thirty years. Its advanced networking, security, and storage features have made FreeBSD the platform of choice for many of the busiest web sites and most pervasive embedded networking and storage devices.
GhostBSD GhostBSD provides a simple desktop-oriented operating system based on FreeBSD with MATE, OpenRC and OS packages for simplicity. GhostBSD has a selection of commonly used software preinstalled and required to start using it to its full potential.
hello helloSystem is a desktop system for creators with a focus on simplicity, elegance, and usability. Its design follows the "Less, but better" philosophy. It is intended as a system for "mere mortals", welcoming to switchers from the Mac. FreeBSD is used as the core operating system. Please refer to https://github.com/helloSystem/hello if you would like to learn more about the ideas and principles behind hello.
Ariyx Airyx is a new open-source desktop operating system that aims to provide a similar experience and compatibiilty with macOSĀ® on x86-64 sytems. It builds on the solid foundations of FreeBSD, existing open source packages in the same space, and new code to fill the gaps. Airyx aims to feel sleek, stable, familiar and intuitive, handle your daily tasks, and provide as much compatibility as possible with the commercial OS that inspired it.
NetBSD NetBSD is a free, fast, secure, and highly portable Unix-like Open Source operating system. It is available for a wide range of platforms, from large-scale servers and powerful desktop systems to handheld and embedded devices.
OpenBSD The OpenBSD project produces a FREE, multi-platform 4.4BSD-based UNIX-like operating system. Our efforts emphasize portability, standardization, correctness, proactive security and integrated cryptography. As an example of the effect OpenBSD has, the popular OpenSSH software comes from OpenBSD.
HAIKU Haiku is an open-source operating system that specifically targets personal computing. Inspired by the BeOS, Haiku is fast, simple to use, easy to learn and yet very powerful.
Illumos illumos is a consolidation of software that forms the core of an Operating System. It includes the kernel, device drivers, core system libraries, and utilities. It is the home of many technologies include ZFS, DTrace, Zones, ctf, FMA, and more. We pride ourselves on having a stable, highly observable, and technologically different system. In addition, illumos traces it roots back through Sun Microsystems to the original releases of UNIX and BSD. see also OmniOS and openindiana.
ArcaOS Arca Noae brings OS/2 into the 21st Century
MorphOS MorphOS is a lightweight, highly efficient and flexible media-centric operating system.
MenuetOS MenuetOS is an operating system for PC, written fully in assembly language (64bit and 32bit). Features include pre-emptive and real-time multitasking with multiprocessor support and Graphical User Interface. Menuet64 is released under License and Menuet32 under GPL. Menuet supports both 64 and 32bit x86 assembly programming for smaller, faster and less resource hungry applications.
ReactOS Imagine running your favorite Windows applications and drivers in an open-source environment you can trust. That's the mission of ReactOS!
Qubes OS Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.
And have a look on following stories
So what is Linux - even if the founder does not like Debian or Ubuntu? - Why Linus Torvalds doesn't use Ubuntu or Debian
Linux != Linux?! Here a (more or less subjective) view from a Linux person: "Why Ubuntu is the Devil and Why So Many No Longer Use It"
A nice look back - I liked Solaris in much ways :) "OpenIndiana 2020.10d"
"12 Reasons to Leave Windows, macOS or Linux - A Vocal Examination"
The good old time :) SUN Ultra 24 - FreeBSD 13 & CDE
Deep Diving Into the Strengths of FreeBSD
Technical reasons to choose FreeBSD over GNU/Linux
MacOS to FreeBSD migration a.k.a why I left macOS
helloSystem: The "Less is More" FreeBSD Desktop
Another nice and new approach of an operating system: HAIKU - with some components based on FreeBSD
Android in FreeBSD bhyve by Oleg
GenoTypeMapper: graphical genotyping on genetic and sequence-based maps - published by Plant Methods
The multi-comparative 2-n-way genome suite - published in Genome Research
NanoPipe: a web server for nanopore MinION sequencing data analysis - published in GigaScience, giy169, doi: 10.1093/gigascience/giy169
GPAC - Genome Presence/Absence Compiler: A Web Application to comparatively visualize multiple genome-level changes - published in Oxford Journals
A Novel Web-Based TinT Application and the Chronology of the Primate Alu Retroposon Activity - published in BMC Evolutionary Biology
Origin of the 1918 pandemic H1N1 influenza A virus as studied by codon usage patterns and phylogenetic analysis - published in Advance November 10, 2010, doi:10.1261/rna.2395211
TEclass: a tool for automated classification of unknown eukaryotic transposable elements
Asset history
1984 - 1985 Study physics at LMU in Munic.
1987 - 1990 Training for "Mathematical Technical Assistent" at FH for Economy in Aachen.
1990 - 1995 Design and implement retrival software in C (with database Progress and Interactive Unix) for tools like cutters and others used in industrial production at Cim Source GmbH in Aachen.
1994 - 2000 Study informatics at RWTH in Aachen.
1994 - 1996 Administrator at Institute for Information Systems (I5) at RWTH in Aachen.
1996 - 1998 Develop database applications for banks in Sybase/SQL at CsG in Aachen.
2000 - 2004 Consultant for Java applications in enterprise environments like CICS, IMS, MQ-Series at SerCon (now IBM) in Dortmund.
2004 - 2007 Digitalize, store and provide access to incoming and outgoing letters. Write Java and PL/1 applications and connect host systems and Java environments at LVM in Münster
2008 - now Design and implement biological software, setup and admininstrate Unix servers and external software at Institute of Bioinformatics (UKM) in Münster
2021-09-15 19:21